WorldCat Identities

Mbulaiteye, Sam M.

Overview
Works: 20 works in 20 publications in 1 language and 38 library holdings
Roles: Contributor, Author, Other
Publication Timeline
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Most widely held works by Sam M Mbulaiteye
A cross-sectional study of asymptomatic Plasmodium falciparum infection burden and risk factors in general population children in 12 villages in northern Uganda by Marlena Maziarz( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Cancer risk in persons with HIV/AIDS in India: a review and future directions for research by Robert J Biggar( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Risk of classical Kaposi sarcoma by plasma levels of Epstein-Barr virus antibodies, sCD26, sCD23 and sCD30 by Colleen Pelser( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

A population-based study of Kaposi Sarcomaassociated herpesvirus seropositivity in Uganda using principal components analysis by Joanne T Chang( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

Infections and cancer: debate about using vaccines as a cancer control tool by Sam M Mbulaiteye( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

Clinical oncology in resource-limited settings by Franco M Buonaguro( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

H. pylori-infection and antibody immune response in a rural Tanzanian population by Sam M Mbulaiteye( )

1 edition published in 2006 in English and held by 2 WorldCat member libraries worldwide

Infectious Agents and Cancer reviewer acknowledgement 2013 by Franco M Buonaguro( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Burkitt lymphoma research in East Africa: highlights from the 9th African organization for research and training in cancer conference held in Durban, South Africa in 2013 by Kenneth O Simbiri( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

HIV and cancer in Africa: mutual collaboration between HIV and cancer programs may provide timely research and public health data by Sam M Mbulaiteye( )

1 edition published in 2011 in English and held by 2 WorldCat member libraries worldwide

Infectious Agents & Cancer reviewer acknowledgement 2012 by Franco M Buonaguro( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

Nonlinear Burkitt lymphoma risk patterns with age and CD4 lymphocyte count among persons with AIDS in the United States by Mercy Guech-Ongey( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Burkitt Lymphoma: beyond discoveries by Sam M Mbulaiteye( )

1 edition published in 2013 in English and held by 2 WorldCat member libraries worldwide

Cancer burden among HIV-positive persons in Nigeria: preliminary findings from the Nigerian AIDS-cancer match study by Sally N Akarolo-Anthony( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

HHV-8 seroprevalence: a global view by Eliane Rohner( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

A case-control study of Burkitt lymphoma in East Africa: are local health facilities an appropriate source of representative controls? by Sonya Baik( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Burkitt lymphoma : a model of polymicrobial carcinogenesis and global oncology by Sam M Mbulaiteye( Visual )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

(CIT): It has been just over 50 years since the description of Burkitt Lymphoma (BL) as an unusual tumor affecting jaws of African children. Seminal discoveries linked to BL include Epstein-Barr virus, the first human virus linked to a human cancer, the linkage of BL to Plasmodium falciparum malaria, chromosomal translocations involving c-Myc and immunoglobulin promoter elements, and demonstration of rapid and curative response to chemotherapy. Dubbed the Rosetta stone of cancer, BL became a complex model for carcinogenesis involving poly-microbes, immunity and host-genetics. Fifty years later, many fundamental questions remain unanswered. Why BL occurs in a small fraction of people chronically exposed to malaria and/or EBV, the risk conveyed by infections singly or jointly, the specific malaria or EBV proteins involved, and whether EBV or malaria have high-risk variants for BL and the pathogen-host interactions involved in BL. In addition, we do not know how to prevent or adequately treat BL. The lecture will dissect the epidemiology of BL, particularly in Africa. It will explore the inherent difficulties quantifying the association of malaria, EBV, and other exposures in human populations in an effort to summarize the strength and weaknesses of the evidence linking EBV and malaria to BL. Borrowing from malaria diagnostic and vaccine studies, the lecture will explore new approaches to quantify risks of association with specific pathogen proteins and insights into pathways potentially exploited to increase or decrease the risk of BL. It will also highlight the potential of proteomics and genomics technologies to slingshot discoveries in BL. Finally, the lecture will offer a panoramic view of BL as a complex model for carcinogenesis and highlight the critical nature of multidisciplinary and international collaboration to engage and build capacity for pediatric oncology research in developing countries where BL is endemic
HIV and cancer registry linkage identifies a substantial burden of cancers in persons with HIV in India( )

1 edition published in 2016 in English and held by 1 WorldCat member library worldwide

Abstract : Abstract: We utilized computerized record-linkage methods to link HIV and cancer databases with limited unique identifiers in Pune, India, to determine feasibility of linkage and obtain preliminary estimates of cancer risk in persons living with HIV (PLHIV) as compared with the general population. Records of 32, 575 PLHIV were linked to 31, 754 Pune Cancer Registry records (1996-2008) using a probabilistic-matching algorithm. Cancer risk was estimated by calculating standardized incidence ratios (SIRs) in the early (4-27 months after HIV registration), late (28-60 months), and overall (4-60 months) incidence periods. Cancers diagnosed prior to or within 3 months of HIV registration were considered prevalent. Of 613 linked cancers to PLHIV, 188 were prevalent, 106 early incident, and 319 late incident. Incident cancers comprised 11.5% AIDS-defining cancers (ADCs), including cervical cancer and non-Hodgkin lymphoma (NHL), but not Kaposi sarcoma (KS), and 88.5% non-AIDS-defining cancers (NADCs). Risk for any incident cancer diagnosis in early, late, and combined periods was significantly elevated among PLHIV (SIRs: 5.6 [95% CI 4.6-6.8], 17.7 [95% CI 15.8-19.8], and 11.5 [95% CI 10-12.6], respectively). Cervical cancer risk was elevated in both incidence periods (SIRs: 9.6 [95% CI 4.8-17.2] and 22.6 [95% CI 14.3-33.9], respectively), while NHL risk was elevated only in the late incidence period (SIR: 18.0 [95% CI 9.8-30.20]). Risks for NADCs were dramatically elevated (SIR> 100) for eye-orbit, substantially (SIR> 20) for all-mouth, esophagus, breast, unspecified-leukemia, colon-rectum-anus, and other/unspecified cancers; moderately elevated (SIR> 10) for salivary gland, penis, nasopharynx, and brain-nervous system, and mildly elevated (SIR> 5) for stomach. Risks for 6 NADCs (small intestine, testis, lymphocytic leukemia, prostate, ovary, and melanoma) were not elevated and 5 cancers, including multiple myeloma not seen. Our study demonstrates the feasibility of using probabilistic record-linkage to study cancer/other comorbidities among PLHIV in India and provides preliminary population-based estimates of cancer risks in PLHIV in India. Our results, suggesting a potentially substantial burden and slightly different spectrum of cancers among PLHIV in India, support efforts to conduct multicenter linkage studies to obtain precise estimates and to monitor cancer risk in PLHIV in India
 
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Audience Level
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  Kids General Special  
Audience level: 0.97 (from 0.88 for HIV and ca ... to 0.97 for Burkitt ly ...)

WorldCat IdentitiesRelated Identities
Alternative Names
Sam M Mbulaiteye wetenschapper

Languages
English (20)