WorldCat Identities

Lincoln, Sarah

Overview
Works: 11 works in 11 publications in 2 languages and 18 library holdings
Roles: Contributor, Author, Editor
Publication Timeline
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Most widely held works by Sarah Lincoln
Dig where you stand by Sarah Lincoln( Book )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

Kein Mut zu mehr Verbindlichkeit Kommentar deutscher Nichtregierungsorganisationen zum Nationalen Aktionsplan Wirtschaft und Menschenrechte der Bundesregierung by Verena Haan( )

1 edition published in 2017 in German and held by 2 WorldCat member libraries worldwide

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels by Alzheimer's Disease Genetics Consortium (ADGC)( )

1 edition published in 2014 in English and held by 2 WorldCat member libraries worldwide

Platinum for the world market, iron shacks for the workers living and working conditions in Marikana five years after the massacre by Aisha Bahadur( Book )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

In vivo silencing of alpha-synuclein using naked siRNA by Jada Lewis( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

Edles Metall - unwürdiger Abbau Platin aus Südafrika und die Verantwortung deutscher Unternehmen by Aisha Bahadur( Book )

1 edition published in 2018 in German and held by 2 WorldCat member libraries worldwide

Lrrk2 pathogenic substitutions in Parkinson's disease by Ignacio F Mata( )

1 edition published in 2005 in English and held by 2 WorldCat member libraries worldwide

Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci by Mariet Allen( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Late-onset Alzheimer disease risk variants mark brain regulatory loci( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Abstract : Objective: To investigate the top late-onset Alzheimer disease (LOAD) risk loci detected or confirmed by the International Genomics of Alzheimer's Project for association with brain gene expression levels to identify variants that influence Alzheimer disease (AD) risk through gene expression regulation. Methods: Expression levels from the cerebellum (CER) and temporal cortex (TCX) were obtained using Illumina whole-genome cDNA-mediated annealing, selection, extension, and ligation assay (WG-DASL) for ∼400 autopsied patients (∼200 with AD and ∼200 with non-AD pathologies). We tested 12 significant LOAD genome-wide association study (GWAS) index single nucleotide polymorphisms (SNPs) for cis association with levels of 34 genes within ±100 kb. We also evaluated brain levels of 14 LOAD GWAS candidate genes for association with 1, 899 cis -SNPs. Significant associations were validated in a subset of TCX samples using next-generation RNA sequencing (RNAseq). Results: We identified strong associations of brain CR1, HLA-DRB1, and PILRB levels with LOAD GWAS index SNPs. We also detected other strong cis- SNPs for LOAD candidate genes MEF2C, ZCWPW1, and SLC24A4 . MEF2C and SLC24A4, but not ZCWPW1 cis -SNPs, also associate with LOAD risk, independent of the index SNPs. The TCX expression associations could be validated with RNAseq for CR1, HLA-DRB1, ZCWPW1, and SLC24A4. Conclusions: Our results suggest that some LOAD GWAS variants mark brain regulatory loci, nominate genes under regulation by LOAD risk variants, and annotate these variants for their brain regulatory effects
The city and state as home-maker : the redevelopment of Ballymun within the context of twentieth-century architectural history by Sarah Lincoln( )

1 edition published in 2004 in English and held by 1 WorldCat member library worldwide

Grundrechte-Report 2021( Book )

1 edition published in 2021 in German and held by 0 WorldCat member libraries worldwide

 
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Audience level: 0.93 (from 0.75 for The city a ... to 1.00 for Grundrecht ...)

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