WorldCat Identities

Rouzioux, Christine

Overview
Works: 31 works in 33 publications in 2 languages and 55 library holdings
Roles: Contributor, Thesis advisor, Other, Author, Opponent
Publication Timeline
.
Most widely held works by Christine Rouzioux
Résistance du VIH-1 aux antirétroviraux dans les réservoirs anatomiques et cellulaires by Jade Ghosn( Book )

2 editions published in 2006 in French and held by 3 WorldCat member libraries worldwide

We showed that HIV resistant strains are frequent (70 %) in the semen of heavily pretreated men, and the diversity of genotypic resistance pattern confirmed HIV compartmentalization. The storage of archived proviruses differed according to the anatomic reservoir. Thus, the risk of transmission of resistant HIV strain is only partially predicted by the study of the blood compartment. We then described the distribution of antiretroviral drugs in blood in semen. We provided the first results regarding the penetration of enfuvirtide and tenofovir in semen. Enfuvirtide did not cross the blood-testis barrier despite optimal concentrations reached in blood plasma. Conversely, tenofovir proved to accumulate in semen. Finally, we characterized the early establishment of the viral cellular reservoir, and to analyse the temporal evolution of resistance-mutations acquired at the time of primary HIV-infection not only in circulating recently produced HIV particles, but also in strains stored in the cellular reservoir, in treated and in untreated patients. We confirmed that acquired resistant viruses establish themselves as the dominant viral population at primary infection
Impact of Counseling Methods on HIV Retesting Uptake in At-Risk Individuals: A Randomized Controlled Study by Nicolas Salvadori( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

The HIV RNA setpoint theory revisited by Ronald Bertus Geskus( )

1 edition published in 2007 in English and held by 2 WorldCat member libraries worldwide

Immunovirological response to combined antiretroviral therapy and drug resistance patterns in children: 1- and 2-year outcomes in rural Uganda by Laurence Ahoua( )

1 edition published in 2011 in English and held by 2 WorldCat member libraries worldwide

Is access to care different for women from sub-Saharan Africa than for French women according to prevention of mother-to-child HIV transmission in France? by ANRS French Perinatal Cohort EPF( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

High prevalence of cytomegalovirus (CMV) infection in infants born to HIV infected mothers-ANRS French Perinatal Cohort (EPF) by ANRS French Perinatal Cohort (EPF)( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

Early diagnosis of HIV-1 infection in newborns, in the context of prevention of mother-to-child transmission with HAART (Perinatal Cohort ANRS Co 01) by Véronique Avettand-Fénoël( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

QUANTIFICATION DU VIH-1 CHEZ L'ENFANT INFECTE PAR TRANSMISSION MATERNO-FOETALE by DOMINIQUE MAYMAT( Book )

1 edition published in 1992 in French and held by 2 WorldCat member libraries worldwide

The frequency of HIV-specific CD8 T lymphocytes is inversely correlated to HIV DNA levels in untreated infected children by Florence Buseyne( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

A guinea pig model for cytomegalovirus congenital infection: dose-effect and vertical transmission rate by Guillaume Benoist( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

Etude de l'établissement des réservoirs VIH lors de la primo-infection et de l'impact des traitements antirétroviraux très précoces sur ces réservoirs by Antoine Chéret( Book )

2 editions published in 2014 in French and held by 2 WorldCat member libraries worldwide

La primo-infection est un moment critique de l'établissement du réservoir justifiant de l'initiation d'un traitement précoce. Nous avons initié un essai randomisé évaluant l'impact de deux ans d'un traitement antirétroviral intense (essai ANRS147 OPTIPRIM, trithérapie versus pentathérapie) sur le réservoir et avons initié des études physiopathologiques au cours de cet essai. Nous montrons ainsi la faible diversité génétique des virus en primo-infection dans les compartiments sanguins et rectaux. Le réservoir s'établit dès le premier mois de l'infection par diffusion d'un cluster viral homogène au sein des lymphocytaires T CD4 naïfs (TN) et mémoires centrales (TCM), transitionnelles (TTM), effectrices (TEM) quiescents. Il en résulte une perturbation de l'homéostasie lymphocytaire associée à une faible contribution au réservoir des cellules peu différenciées à longue demi-vie, TN et TCM. Par ailleurs nous montrons que la majorité des patients au moment de leur primo-infection n'ont pas la capacité de développer des réponses T CD8 à même de supprimer la réplication virale comme chez les patients HIV Controllers. Après deux ans de traitement, nous observons que la diversité virale n'a pas évolué, par contre la taille du réservoir est fortement réduite. Les anomalies de l'homéostasie lymphocytaire T CD4 persistent, par contre le traitement très précoce a permis de protéger les TN et TCM. Il n'y a pas de bénéfice additionnel d'une pentathérapie mais nous avons validé le concept qu'un traitement précoce permet d'induire un contrôle virologique au long cours après arrêt de traitement. Nos résultats indiquent qu'un traitement plus long que deux ans permettrait de renforcer la diminution du réservoir. Ces résultats seront à prendre en compte pour l'élaboration de futurs essais en primo-infection visant à réduire le réservoir pour une rémission au long cours
Very early diagnosis of HIV infection in newborn at day 0-day 3 on DBS in Cambodia by Sopheak Ngin( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Développement d'une technique ELISA pour la détection et le titrage des IgG anti-LAV (Lymphadenopathy-associated-virus) le nouveau rétrovirus humain responsable du SIDA by Christine Rouzioux( Book )

1 edition published in 1985 in French and held by 2 WorldCat member libraries worldwide

Perinatal transmission of Cytomegalovirus (CMV) in children born to HIV positive and negative women in Cameroon by Anfumbom Kfutwah( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Early diagnosis of HIV-1 infection in Cambodian infants by Sopheak Ngin( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

New and old complex recombinant HIV-1 strains among patients with primary infection in 1996-2006 in France: The French ANRS CO06 primo cohort study by Pierre Frange( )

1 edition published in 2008 in English and held by 2 WorldCat member libraries worldwide

Is marital status and information of the father associated with access to prevention of mother-to-child HIV transmission? by Carine Jasseron( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

Spatiotemporal dynamics of HIV-1 transmission in France (1999-2014) and impact of targeted prevention strategies by On behalf the ANRS PRIMO Cohort Study( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

 
moreShow More Titles
fewerShow Fewer Titles
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.96 (from 0.93 for Etude de l ... to 0.97 for Résistanc ...)

WorldCat IdentitiesRelated Identities
Alternative Names
Calmettes, Christine

Christine Rouzioux hulumtuese

Christine Rouzioux researcher

Christine Rouzioux viróloga francesa

Кристин Рузью

Languages
English (16)

French (6)