WorldCat Identities

Faivre, Damien

Overview
Works: 3 works in 4 publications in 1 language and 4 library holdings
Roles: Opponent, Author, Other
Publication Timeline
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Most widely held works by Damien Faivre
Propriétés cinétiques, minéralogiques et isotopiques de la formation de nanomagnétites à basse temperature : implication pour la détermination de critères de biogénicité by Damien Faivre( Book )

2 editions published between 2004 and 2007 in French and held by 2 WorldCat member libraries worldwide

Greigite et magnétite : les déterminants environnementaux et génétiques contrôlant la biominéralisation chez les bactéries magnétotactiques by Elodie Descamps( )

1 edition published in 2018 in French and held by 1 WorldCat member library worldwide

Magnetotactic bacteria represent a phylogenetically and ecologically diverse group of prokaryotes able to biomineralize magnetic nanocrystals composed of magnetite [an iron oxide (Fe(II)Fe(III)2O4)] or greigite [an iron sulfide (Fe(II)Fe(III)2S4)] in their magnetosomes, a prokaryotic organelle whose cytoplasmic alignement in chain allows the cell to navigate along the Earth's magnetic field lines. Until recently, only magnetite-producing strains were available in pure culture. Thus, only the magnetite biomineralization has been studied. In 2011, a new bacterium able to form both magnetite and greigite, Desulfamplus magnetovallimortis strain BW-1, was isolated from Death Valley, California and cultivated in pure culture. In this work, we propose to use an integrated and multidisciplinary approach to understand the mechanisms involved in greigite biomineralization in BW-1 strain. First, we determined the environmental and biological conditions in which magnetite and greigite are formed. This first part of my thesis also contributed to the physiologic and phylogenetic characterization of this bacterium. Secondly, we used global and targeted transcriptomic approaches to evaluate the transcription levels of genes putatively involved in magnetosomes formation (magnetite vs. greigite) under various growth conditions. A proteomic approach provided additional informations to this study.Results obtained during my thesis contribute to the understanding of in vivo biomineralization, particularly for greigite production in magnetotactic bacteria
Nanoparticules en environnement cellulaire : Impact de la nano-architecture sur l'internalisation, la biodégradation et les fonctionnalités thérapeutiques. by Anouchka Plan( )

1 edition published in 2019 in French and held by 1 WorldCat member library worldwide

Inorganic nanoparticles represent innovative solution to face current limitations in early diagnostic or targeted therapies.First part focuses on the interactions between magnetic nanoparticles and stem cells to understand better the parameters which impact internalization and biodegradation. We evidenced an impact from the nanoparticle's coating, the presence of proteins and the aggregation. Nanoparticles' impact on cellular differentiation shown a process of re-magnetization of the iron products of degradation for some differentiation ways.In the second part, we studied anti-cancerous hyperthermal therapies and more precisely the impact of the intracellular confinement. We shown that the cellular environment can completely inhibit the heating delivered by magnetic hyperthermia but at the contrary can also be beneficial for applying photothermia at biocompatible wavelengths. Finally, the combination of photothermia with a drug leaded to an increase of the efficiency of both therapies separated with reduces secondary effects
 
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Audience level: 0.96 (from 0.93 for Propriéte ... to 0.99 for Propriéte ...)

Languages
French (4)