WorldCat Identities

Keller, Matthieu

Overview
Works: 18 works in 23 publications in 3 languages and 528 library holdings
Genres: Juvenile works 
Roles: Author, Contributor, Other, Thesis advisor, Opponent, Editor
Publication Timeline
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Most widely held works by Matthieu Keller
Les animaux et le sexe : 60 clés pour comprendre by Matthieu Keller( )

4 editions published in 2018 in French and held by 503 WorldCat member libraries worldwide

Etre fier comme un paon ou chaud comme un lapin ou monté comme un cheval ! Autant d'expressions de bon ou mauvais goût qui témoignent de l'empreinte que les animaux et leurs comportements sexuels ont laissée dans notre imaginaire. Et il y a de quoi ! Car entre des poissons qui changent de sexe, des canards avec un zizi en tire-bouchon, des araignées mâles qui abandonnent leur organe copulatoire dans la femelle pour assurer leur paternité ou des moutons aux comportements homosexuels...le Kamasutra animal n'en finit pas de nous étonner par sa prodigieuse (bio)diversité ! Les signaux émis en période de reproduction, que ce soit le chant mélodieux des oiseaux, la parure colorée de certains poissons, ou les odeurs émises par diverses espèces de papillons de nuit, n'ont d'autres buts que d'attirer et de séduire le partenaire sexuel. Qu'elle soit à poils, à plumes ou à écailles, la vie sexuelle des bêtes nous révèle une histoire naturelle improbable où les bêtes de sexe ne sont pas toujours celles que l'on croit. Ainsi, un costaud comme l'éléphant n'honore sa dame que tous les cinq ans en moyenne, alors que la punaise dite justement... "de lit" peut avoir plus de 200 rapports sexuels par jour ! N'oublions pas que la reproduction animale sert par ailleurs la société humaine... Procréation médicale assistée, recherche de traitements contre l'autisme, différenciation sexuelle, préservation de la biodiversité... autant de questions et de débats qui animent nos sociétés actuelles en médecine, agronomie, éthique ou écologie. En un mot, au sein de l'arche de Noé, sauter du coq à l'âne fait plus de sens qu'il n'y paraît !
<> by Livio Oboti( )

2 editions published in 2014 in English and held by 4 WorldCat member libraries worldwide

Processus d'acquisition et de consolidation impliqués dans la mémorisation des caractéristiques multisensorielles du jeune par la brebis : approches comportementale et neurobiologique by Matthieu Keller( Book )

2 editions published in 2003 in French and held by 3 WorldCat member libraries worldwide

Chez les ovins, la mère reconnaît l'odeur de son jeune juste après la parturition et restreint alors l'allaitement à cet agneau. L'objectif de cette thèse est de caractériser la dynamique d'apprentissage et de rétention de la reconnaissance de l'agneau ainsi que les structures neurobiologiques impliquées. La reconnaissance olfactive de l'agneau est fonctionnelle en 2h post-parfum et lors de cet apprentissage, l'expression de la protéine Fos révèle que diverses structures sont activées, notamment le noyau cortical de l'amygdale, L'inaction de ce noyau ainsi que celle du noyau médian par un anesthésique, entraîne un déficit de reconnaissance. Enfin, au cours du temps de contact mère-jeune, une reconnaissance durable de l'agneau se met en place. Elle s'accompagne d'une activation de la protéine Fos plus marquée dans les cortex frontaux lors du rappel. Cette étude a montré l'importance des structures limbiques dans l'acquisition de la mémoire et des structures corticales dans son rappel
Adult male mice exposure to nonylphenol alters courtship vocalizations and mating by Daphné Capela( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

The olfactory secretome varies according to season in female sheep and goat by Paul Cann( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Is the Loss of Trpc2 Gene Function a Real Working Hypothesis for the Emergence of Same-Sex Sexual Behavior in Old World Primates? by Matthieu Keller( )

1 edition published in 2020 in English and held by 2 WorldCat member libraries worldwide

Editorial by Matthieu Keller( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Plasticité moléculaire de l'aire pré-optique médiane de l'hypothalamus induite par l'expérience sexuelle chez la souris mâle by Arnaud Jean( )

1 edition published in 2017 in French and held by 1 WorldCat member library worldwide

Sexually experimented males exhibit long term modifications of the dendritic arborization, epigenetic modifications and increased levels of microglia and glutamate associated protein within the hypothalamic medial preoptic area (mPOA). However, hypothalamic and plasmatic concentration of steroid hormones and the nitrergic system are not impacted, contrary to data obtained in rat.The involvement of the ERK1/2 signaling pathway in the induction of sexual experience has also been studied. We showed that ERK1/2 pathway was activated within the mPOA during mating. This activation was increased in sexually experienced males. Furthermore, we showed ex vivo on hypothalamic slices that sex steroids were capable of rapidly (30 min) activate this pathway. Finally, the inhibition of ERK1/2 phosphorylation before the first mating did not disrupt the induction of sexual experience but decreased sexual motivation in a reversible manner.Taken together, these results indicate that long lasting and transitory plasticity mechanisms leading to sexual experience are different between rat and mouse. This indicate the necessity to elaborate a new molecular model associated with the behavioral improvement induced by sexual experience in male mouse
Pheromonal communication in higher vertebrates and its implication for reproductive function( Book )

1 edition published in 2009 in English and held by 1 WorldCat member library worldwide

Agressivité et résolution des conflits chez un hyménoptère parasitoïde solitaire, Eupelmus vuilleti : étude des stratégies comportementales et de leur médiation hormonale by Anthony Mathiron( )

1 edition published in 2019 in French and held by 1 WorldCat member library worldwide

Within the animal kingdom, individuals of the same species are often in conflict for access to certain resources. In solitary parasitoids, females can compete directly for access to a host that is an essential resource for their reproductive success. During this thesis, we investigated the factors that influence the display of agonistic behaviour and the outcome of contest over host in females of the solitary parasitoid wasp Eupelmus vuilleti. More specifically, we investigated the effect of host value: a larva or pupa of the cowpea seed beetle, Callosobruchus maculatus. Moreover, we tested whether the genetic relatedness between contestants plays a role in the avoidance of competition and conflict resolution. We also investigated the hormonal mediation of aggressiveness during conflict, focusing on two families of hormones already known to regulate different life history traits and behaviours in adult insects: juvenile hormone and ecdysteroids
Accélération de la puberté par les phéromones mâles chez la souris femelle : régulation des neurones à Kisspeptine et conséquences à long terme sur le comportement sexuel by Mélanie Jouhanneau( )

1 edition published in 2014 in French and held by 1 WorldCat member library worldwide

Chez la souris, la puberté de la femelle est accélérée par des phéromones urinaires émises par le mâle (effet Vandenbergh). Les mécanismes neuroendocriniens sous-Jacents et les conséquences comportementales restent peu connus. Par une approche multidisciplinaire alliant immunohistochimie, chromatographie gazeuse couplée à la spectrométrie de masse et chirurgie expérimentale, mon travail de thèse montre que les neurones synthétisant la kisspeptine, un neuropeptide hypothalamique jouant un rôle essentiel dans le contrôle de la puberté, sont régulés positivement par les phéromones accélératrices de la puberté. Les neurones à kisspeptine reçoivent le signal phéromonal via le système olfactif accessoire et le transmettent aux neurones à GnRH. De plus, des analyses comportementales montrent qu'outre leur effet physiologique connu, les phéromones accélératrices de la puberté modifient à long terme le comportement sexuel de la souris femelle. En effet, la préférence de la femelle pour l'odeur du mâle s'exprime plus tôt à l'âge adulte après l'exposition péripubère aux phéromones émises par la souris mâle
Characterizing the Cellular and Molecular Effects of Neural Androgen Receptor Invalidation in Male Mice by Nida Karameh( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

The crucial role of sex steroid hormones in male reproductive and non-reproductive functions are well documented. Recent evidences suggest that testosterone is also involved in neuroprotective functions in the adult male brain in both pathophysiological and physiological conditions. In the nervous system, testosterone can directly act on the androgen receptor (AR) or be metabolized into estradiol, which then stimulates estrogen receptors (ERs). The expression of these sex steroid receptors is not limited to brain regions implicated in reproductive functions, it expands to other regions such as the hippocampus, cortex that are implicated in cognitive functions. In this context, the signalling pathways underlying testosterone-induced effects, in particular at the neural level, still need to be documented. For this purpose, we used a conditional transgenic mouse line lacking the neural AR in order to identify the molecular and cellular targets of testosterone. First, a proteomic analysis was undertaken in the preoptic area, the hypothalamic region involved in the expression of male sexual behavior, in order to identify the molecular targets of the AR. In this study, several differentially expressed proteins were identified, and validation was conducted for a subset of top ten proteins identified by Ingenuity Pathway Analysis. Second, analysis of neuroinflammation and BBB integrity was performed in the same region. Deletion of neural AR (in neurons and glial cells) led to neuroinflammation as evidenced by astroglial activation and increased Fluorojade labeling. This was associated with BBB leakage for different tracers and endogenous immunoglobulin and by disorganization of the tight junction structures shown by electron tomography in mutant males.Altogether, the present data will provide and help gain new insights into the cellular effects and molecular signalling pathways involved in neural effects of testosterone
Induction d'une maturation sexuelle précoce chez la chevrette par une exposition prépubertaire au mâle by Manon Chasles( )

1 edition published in 2017 in French and held by 1 WorldCat member library worldwide

Chez les rongeurs, les facteurs sociaux sont connus pour pouvoir moduler la transition pubertaire. Ainsi une jeune souris femelle mise en contact avec un mâle adulte présentera une ouverture vaginale plus précoce qu'une femelle isolée du mâle. L'objectif de ma thèse a été de caractériser les conséquences d'une exposition précoce au mâle dans l'espèce caprine. Les caprins sont une espèce dont la reproduction est saisonnée et permettant, de par sa taille, une étude plus fine des sécrétions endocrines que les rongeurs. Nos résultats ont permis de mettre en évidence que la présence de boucs sexuellement actifs induit une puberté précoce chez les chevrettes, l'ovulation pouvant être induite dès l'âge de 3 mois et demi. Les femelles présentent suite à cette première ovulation une cyclicité régulière ainsi qu'une maturation précoce du tractus génital. Le niveau d'activité sexuelle du bouc est un facteur crucial à l'induction d'une puberté précoce chez la chèvre puisque la présence de mâles castrés n'a aucun effet et que les femelles sont toutes pubères dans le mois suivant l'entrée en saison sexuelle des mâles. Ce travail démontre, dans l'espèce caprine, un rôle crucial de l'environnement social dans la régulation de la maturation sexuelle. Plus particulièrement, cela met en évidence que la présence de boucs peut réactiver efficacement et de manière très précoce l'axe gonadotrope de jeunes chèvres immatures
Gestion de populations de rongeurs dans un contexte leptospirosique by Aurélie Marquez( )

1 edition published in 2019 in French and held by 1 WorldCat member library worldwide

Management of rodent populations is important because they can cause various economic, ecologic and health problems. This management relies on prevention methods, these ones being architectural, hygienic and agricultural practices. It relies on biologic, chemical and mechanic control methods. Chemical control methods are made mainly with the use of anticoagulant rodenticide acting several hours after ingestion to provide food eviction. Excessive use of these molecules led to resistance selection of some individuals yielding their use underperforming. Then there has been new molecules development, but they are more ecotoxic. In these thesisworks we are interested in management of rodent populations within a framework of health risk of leptospirosis. Rodents are main reservoirs of pathogenic leptospires, Spirochete bacterias responsible of leptospirosis. Leptospirosis is a worldwide re-emerging zoonosis of which there are approximately one million of cases each year and of which there is an increasing number of cases these last years. It is endemic in tropical regions. It is a disease of which real incidence is underestimated because of especially large variability of possible symptoms ranging from flu syndrome to renal forms. Mortality rate is high around 10% and up to 50% in certain cases with pulmonary complications. Numerous factors influence on complex transmission cycle of leptospirosis. There can be health risk associated with presence of rodent carriers of pathogenic leptospires, which can be difficult to control if rodents are resistant to anticoagulant rodenticides used to regulate their populations. Furthermore, there can have exposition problems to ecotoxic risks throughout establishment of chemical treatment. We studied several concrete cases showing the difficulty in decision-making relied with rodent management in various contexts. In a context of economic problems, we analysed pathogenic leptospires carriage by meadow voles and ground voles as well as target resistance to bromadiolone, used molecule in chemical control of low population density. We are interested in influence of societal perception on health risk relied with mice in bovine farming in which there are human and bovine leptospirosis cases. In framework of a project leading to study efficiency of commensal rodent populations management in Martinique in a leptospirosis context, we looked rodent exposition to AVKs and target resistance to AVKs. For pathogenic leptospires carriage by voles we found prevalence ranging from 3% to 53% according to studied area. There were 3 mutations on vkorc1 gene leading to few target resistances to bromadiolone. In the bovine farming we found especially that societal perception of the breeder underestimated risk relied with mice of which 41% were carriers of pathogenic leptospires and 50% were carriers of vkorc1 gene mutations leading to target resistance to AVKs. In Martinique we found that 54% of analysed individuals have been exposed to at least one AVKs molecules and that there were several vkorc1 gene mutations in which certain were not characterised yet leading to target resistance to AVKs. Rodent management is a complex problem with several factors to take into account whether risks relied with rodent exposition or those relied with the use of anticoagulant rodenticides. Furthermore, the concept of risk is scientific but the perception which is subjective participates in decision-making of a way of management
Les animaux et le sexe : 60 clés pour comprendre by Matthieu Keller( )

1 edition published in 2018 in French and held by 1 WorldCat member library worldwide

Entre des poissons qui changent de sexe, des canards avec un zizi en tire-bouchon, des araignées mâles qui abandonnent leur organe copulatoire dans la femelle pour assurer leur paternité ou des moutons aux comportements homosexuels? le Kamasutra animal n'en finit pas de nous étonner par sa prodigieuse (bio)diversité. Tout ce que vous avez toujours voulu savoir sur le sexe à poils, à plumes ou à écailles !
La réduction du temps de contact entre mâles et femelles ne diminue pas les réponses ovulatoire et reproductive de chèvres à l'effet mâle pendant l'anoestrus by Marie Bedos( )

1 edition published in 2013 in Spanish and held by 1 WorldCat member library worldwide

Seasonality of reproduction consists of alternations between periods of sexual activity and sexual rest (anoestrus). This seasonality is observed in goats from subtropical Mexico and makes impossible out-of-season reproduction. The reintroduction of a male in a group of females can break the seasonal anoestrus and quickly stimulate ovarian activity. However, the use of bucks induced to a high sexual activity during the sexual rest by a treatment of long days -photo-stimulated males- is necessary to ensure the quality of stimulation provided by them. The duration of contact between sexes is another factor that modulates the response of females and it has long been suggested that it should be maintained continuously (24h/24) for several days so that the majority of females ovulate. The purpose of this thesis was to determine whether a reduction of daily contact between sexes decrease ovulatory and reproductive responses of goats exposed to males during the seasonal anoestrus. The results indicate that duration of contact between sexes can be drastically reduced from 16 to 1 h per day without reducing the ovulatory and reproductive responses of females
Les animaux et le sexe : 60 clés pour comprendre by Matthieu Keller( )

1 edition published in 2018 in French and held by 1 WorldCat member library worldwide

Entre des poissons qui changent de sexe, des canards avec un zizi en tire-bouchon, des araignées mâles qui abandonnent leur organe copulatoire dans la femelle pour assurer leur paternité ou des moutons aux comportements homosexuels? le Kamasutra animal n'en finit pas de nous étonner par sa prodigieuse (bio)diversité. Tout ce que vous avez toujours voulu savoir sur le sexe à poils, à plumes ou à écailles !
Environnement socio-olfactif et choix alimentaires chez la souris domestique, Mus musculus domesticus by Tatiana Forestier( )

1 edition published in 2018 in English and held by 0 WorldCat member libraries worldwide

The ecological success of the house mouse, Mus musculus domesticus, implies a great capacity to adapt its diet to available food resources. The social transmission of food preference (STFP) is an adaptive type of learning observed in rodents allowing them to enlarge their food repertoire at lower risk by getting olfactory information on novel food sources from conspecifics. This social learning takes place directly, during an encounter with a conspecific or indirectly, via olfactory marks. The objective of this thesis work was to determine how mice use their socio-olfactory environment to make food choices. Our results revealed that the absence of the conspecific during the indirect STFP reduces the social constraints associated with an encounter and allows the acquisition of STFP between unfamiliar conspecifics. However, some physical constraints associated with the perception of information in feces may reduce the availability of food information. We also showed that different sex concerns of individuals may affect the prioritization of information present in feces and limit, in males, the acquisition of STFP. Our results suggest that the use of food information in mice varies according to their social and ecological context and involves different processes such as emotion and attention. Under natural conditions, the direct and indirect STFP could be complementary, each of them extending the conditions for the transmission of food information in rodents
 
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Matthieu Keller researcher

Matthieu Keller wetenschapper

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